Objectives: The onset of the 2020 coronavirus pandemic resulted in rapid implementation of virtual care solutions at an unprecedented pace.The news media, as a trusted source for many Canadians, plays a vital role during emergencies by reporting on changes Stethoscopes in health care protocols, policies, and technologies.This article presents the r
Aerodynamic Load Prediction on a Patrol Vessel Using Computational Fluid Dynamics
Aerodynamic loads and moments on a naval patrol vessel are investigated using computational fluid dynamic simulations based on the OpenFOAM solver.After the initial turbulence, time, and grid dependency study, model scale simulations were performed for a wide range of inflow angles to predict aerodynamic forces Stethoscopes and moments acting on th
A Physiologically Based Pharmacokinetic Framework for Quantifying Antibody Distribution Gradients from Tumors to Tumor-Draining Lymph Nodes
Immune checkpoint blockades prescribed in the neoadjuvant setting are now under active investigation for many types of tumors, and many have shown early success.The primary tumor (PT) and tumor-draining lymph node (TDLN) immune factors, along with adequate therapeutic antibody distributions to the PT and TDLN, are critical for optimal immune activa